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Key Considerations for Mixing DDR3 8GB RAM

Performance Impact: When RAM sticks with different speeds are mixed, the system will operate at the speed of the slowest stick.
System Stability: Mixing brands or capacities can lead to instability, though it often works in modern systems.
Capacity Combination: You can use 8GB and 4GB sticks together, though this is less efficient than using two identical sticks.
Voltage: It is highly recommended that mixed RAM sticks share the same voltage rating.
Optimal Approach: For best results, use identical modules (same brand, speed, and capacity) to ensure reliable performance.
Laptop vs. Desktop: Ensure you are using the correct form factor—either SODIMM for laptops or DIMM for deskto

Mixing DDR3 8GB RAM sticks from different brands, speeds, or capacities is possible but generally not recommended, as it can cause system instability or prevent booting. While they often work together by defaulting to the slowest speed, you should ideally match CAS latency, voltage, and frequency for optimal performance and stability.